Aji Handoko, Yoga and Semuel Rondonuwu, Ferdy and Limantara, Leenawaty (2015) The Photosensitizer Stabilities of Tookad® on Aggregation, Acidification, and Day-Light Irradiation. Procedia Chemistry Elsevier, 14. pp. 474-83.
Full text not available from this repository. (Request a copy)Abstract
Tookad® (Pd-Bpheid) as bacteriochlorophylls derivative is third generation of photosensitizer having great promises and efficacy for some cancers treatment. The understanding of the photosensitizer stability in vitro is important and fundamental studies before photodynamic therapy (PDT) pre-clinical treatment, especially their responses to aggregation, acidification, and irradiation. Tookad® stability testing was performed by spectroscopic methods using Varian Cary 50 UV-Vis and Light-Volpi Intralux 1200. The result shows that Tookad® aggregated by water titration and degradation is due to the acidification and day-light irradiation. The day-light irradiation caused Tookad® degradation on Soret and Qy band. The degradation product indicates 3-Acetil-chl and Chlorin.
| Item Type: | Artikel |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Fakultas Teknologi dan Desain > Teknik Sipil |
| Depositing User: | Admin Repository |
| Date Deposited: | 17 Apr 2020 15:39 |
| Last Modified: | 02 Jun 2022 07:15 |
| URI: | http://eprints.upj.ac.id/id/eprint/102 |
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